Crystal Structure Determination of Biological Macromolecular Assemblies; From Data Collection to Structure Determination

摘要

Recent progresses in crystallography on biological macromolecules enable us to solve the atomic structure of the huge macromolecule assemblies. High-brilliance synchrotron radiation and a high-performance area detector are essential for high-quality diffraction data collection from a small-size crystal. Newly developed software for crystal structure determination can be used for quick and accurate structure determination. In this paper, we will review the recent progress in crystallography on biological macromolecular assemblies.