著明な破砕赤血球により為性血小板増多が認められたTMA症例

摘要

A patient with acute lymphocytic leukemia (ALL) experienced severe thrombotic microangiopathy (TMA) after allo-bone marrow transplantation (BMT).She had high risk for TMA; due to total body irradiation (TBI),intensive chemotherapy, treatment with Ciclosporin and association with veno-occlusive disease (VOD). Markedly increased fragmentations of red blood cells were observed in this case,and were incorrectly counted as platelets by a fully automated blood cells counter.Careful evaluation of the platelet count is necessary in patients with red cell fragmentations.