Biotransformations - Part XLVI - Apple-tree shoots and transformed carrot and apple roots used as biocatalysts in enantioselective acetate hydrolysis, alcohol oxidation and ketone reduction

摘要

(+/-)-1-Phenylethyl (1), (+/-)-1-(1-naphthyl)ethyl (2), (+/-)-1-(2-naphthyl)ethyl (3) and (+/-)-menthyl (4) acetates were hydrolyzed using apple-tree shoots and hairy roots of carrot and apple-tree to afford alcohols, which, subsequently, in the same environment, were oxygenated to ketones. Pure (S)-1-(2-naphthyl)ethanol ((S)-(-)-7), (R)-1-phenylethyl acetate ((R)-(+)-1), (R)-1-(1-naphthyl)ethyl acetate ((R)-(+)-2), (S)-1-phenylethanol ((S)-(-)-5) and (-)-menthol (1R,2S,5R)-(-)-8) have been produced. [References: 16]