A case of liver metastasis of colon cancer demonstrating complete remission with combination chemotherapy of 5'-DFUR and MMC

摘要

The patient was a 77-year-old man with advanced colon cancer and liver metastasis, who underwent right hemicolectomy and liver resection. After surgery, a new liver metastasis was found. Chemotherapy of 5'-deoxy-5-fluorouridine (5'-DFUR) and mitomycin C (MMC) was conducted for 6 months. 5'-DFUR was administered orally at 1,200 mg/day for 5 days/week in combination with intravenous administration of MMC at 10 mg/4-week. The treatment was effective and the lesion disappeared. The patient received a subsequent single administration of 5'-DFUR, and remained in remission for 3 years after surgery.