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Persistent lipid abnormalities in patients with hypertension and dyslipidemia treated with statins: results of the Portuguese hypertensive subpopulation of the Dyslipidemia International Study (DYSIS)

机译:他汀类药物治疗的高血压和血脂异常患者的持续脂质异常:国际血脂异常研究(DYSIS)的葡萄牙高血压亚群的结果

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摘要

This study aimed to assess the treatment patterns and prevalence of persistent lipid abnormalities in Portuguese hypertensive patients concomitantly treated with statins. Only 25% of the 656 hypertensive patients achieved the blood pressure goals in use during the study period. Similarly, only 33% and 37% attained the recommended levels of total cholesterol <4.5 mmol/L and LDL cholesterol <2.5 mmol/L, respectively. Relatively low doses of medium potency statins were the mainstay of therapy. There seems to be considerable room for improvement through the use of more potent statins, dose up-titration, and/or addition of other lipid-modifying therapies.
机译:本研究旨在评估葡萄牙他汀类药物同时治疗的高血压患者的持续脂质异常的治疗方式和患病率。在研究期间,656名高血压患者中只有25%达到了使用中的血压目标。同样,分别只有33%和37%的人分别达到建议的总胆固醇<4.5 mmol / L和LDL胆固醇<2.5 mmol / L的水平。低剂量的中度他汀类药物是治疗的主要手段。通过使用更有效的他汀类药物,提高剂量和/或添加其他脂质修饰疗法,似乎还有很大的改进空间。

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