Exogenous carcinoembryonic antigen-related cell adhesion molecule 1 suppresses 2,4,6-trinitrobenzene sulfonic acid-induced ulcerative colitis in mice

Jin Yu; Lin Lianjie; Lin Yan; Zheng Changqing

首页> 外文期刊>Journal of Surgical Research: Clinical and Laboratory Investigation >Exogenous carcinoembryonic antigen-related cell adhesion molecule 1 suppresses 2,4,6-trinitrobenzene sulfonic acid-induced ulcerative colitis in mice

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Exogenous carcinoembryonic antigen-related cell adhesion molecule 1 suppresses 2,4,6-trinitrobenzene sulfonic acid-induced ulcerative colitis in mice

机译：外源癌胚抗原相关细胞粘附分子1抑制小鼠2,4,6-三硝基苯磺酸诱导的溃疡性结肠炎

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Background: Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is known to play an immunomodulatory role in a variety of tumors, but its role in ulcerative colitis (UC) remains to be elucidated. The present study aimed to investigate the effects of exogenous CEACAM1 on UC using a mouse model.

机译：背景：癌胚抗原相关细胞粘附分子1（CEACAM1）在多种肿瘤中起免疫调节作用，但其在溃疡性结肠炎（UC）中的作用尚待阐明。本研究旨在使用小鼠模型研究外源性CEACAM1对UC的影响。

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《Journal of Surgical Research: Clinical and Laboratory Investigation》 |2015年第1期|共8页
作者
Jin Yu; Lin Lianjie; Lin Yan; Zheng Changqing;
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正文语种 eng
中图分类外科学;
关键词
Ulcerative colitis; CEACAM1; Inflammation; Apoptosis;

机译：溃疡性结肠炎;CEACAM1;炎症;凋亡;

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1. Exogenous carcinoembryonic antigen-related cell adhesion molecule 1 suppresses 2,4,6-trinitrobenzene sulfonic acid-induced ulcerative colitis in mice [J] . Jin Yu, Lin Lianjie, Lin Yan, Journal of Surgical Research: Clinical and Laboratory Investigation . 2015,第1期

机译：外源癌胚抗原相关细胞粘附分子1抑制小鼠2,4,6-三硝基苯磺酸诱导的溃疡性结肠炎
2. Chronic inflammation up-regulates P-gp in peripheral mononuclear blood cells via the STAT3/Nf-κb pathway in 2,4,6-trinitrobenzene sulfonic acid-induced colitis mice [J] . Jiali Liu, Fang Zhou, Qianying Chen, Scientific reports. . 2015,第1期

机译：慢性炎症通过STAT3 /Nf-κb途径上调2,4,6-三硝基苯磺酸诱导的结肠炎小鼠的外周单个核血细胞中的P-gp
3. Chronic inflammation up-regulates P-gp in peripheral mononuclear blood cells via the STAT3/Nf-κb pathway in 2,4,6-trinitrobenzene sulfonic acid-induced colitis mice [J] . Jiali Liu, Fang Zhou, Qianying Chen, Scientific reports. . 2015,第1期

机译：慢性炎症通过STAT3 /Nf-κb途径上调2,4,6-三硝基苯磺酸诱导的结肠炎小鼠的外周单个核血细胞中的P-gp
4. Cell adhesion molecules-targeted polymeric worm micelles as selective in vivo drug delivery systems against endothelial cells [C] . Marc A. Ilies, Younghoon Kim, Vladimir V. Shuvaev PMSE Symposia . 2007

机译：细胞粘附分子靶向聚合物蠕虫胶束作为针对内皮细胞的体内药物递送系统中的选择性
5. Carcinoembryonic antigen cell adhesion molecule 1: Cancer and metabolic regulation. [D] . Leung Yu Hing, Nelly. 2008

机译：癌胚抗原细胞粘附分子1：癌症和代谢调节。
6. NCX-1015, a nitric-oxide derivative of prednisolone, enhances regulatory T cells in the lamina propria and protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis in mice [O] . Stefano Fiorucci, Elisabetta Antonelli, Eleonora Distrutti, 2007

机译：NCX-1015，泼尼松龙的一氧化氮衍生物，可增强固有层中的调节性T细胞并预防2,4,6-三硝基苯磺酸诱发的小鼠结肠炎
7. Chronic inflammation up-regulates P-gp in peripheral mononuclear blood cells via the STAT3/Nf-κb pathway in 2,4,6-trinitrobenzene sulfonic acid-induced colitis mice [O] . Jiali Liu, Fang Zhou, Qianying Chen, 2015

机译：慢性炎症通过STAT3 / NF-κB途径在2,4,6-三硝基苯磺酸诱导的结肠炎小鼠中调节外周单核血细胞P-GP

Exogenous carcinoembryonic antigen-related cell adhesion molecule 1 suppresses 2,4,6-trinitrobenzene sulfonic acid-induced ulcerative colitis in mice

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