Anastomotic Recurrence of Colon Cancer: Genetic Analysis Challenges the Widely Held Theories of Cancerous Cells' Intraluminal Implantation and Metachronous Carcinogenesis

摘要

Background and Objectives: Anastomotic recurrence (AR), whose etiopathogenesis is attributed to intraluminal implantation of cancerous cells or metachronous carcinogenesis, is a major issue for patients undergoing colon cancer (CC) resection. The objective of the study is to throw some light on AR etiopathogenesis and to identify risk factors of AR in selecting patients to undergo early endoscopy.