High performance liquid chromatography for facile analytical separation of the enantiomers of chiral organometallic complexes

摘要

The applicability of chiral HPLC for the rapid analysis of the enantiopurity of organoiridium and -molybdenum complexes is demonstrated. Halogen-substituted metal complexes showed the best separation and the longest elution times. Separation of enantiomers of planar chiral zirconium and titanium complexes was also attempted although unsuccessfully. Preparative-scale columns were shown to be useful for the separation of racemic material into synthetically useful amounts of pure enantiomers. (C) 2001 Elsevier Science B.V. All rights reserved. [References: 15]