Splenic scintigraphy for further differentiation of unclear Ga-68-DOTATOC-PET/CT findings: Strengths and limitations

摘要

Splenic scintigraphy has been described to be a powerful tool in unclear Ga-68-DOTATOC-PET/CT findings, allowing differentiation between somatostatin receptor ( Sst)-positive tissue deriving from neuroendocrine tumour ( NET) and functioning splenic tissue. However, our own experiences sometimes show a lack of identification on splenic scintigraphy, especially in small lesions, leading to uncertainties regarding the safe identification of NET or splenic tissue. Here, we report on 10 cases with Ga-68-DOTATOC-PET/CT and Tc-99m-heat-denaturated red blood cell ( HDRBC) scintigraphy and we illustrate the strengths and limitations of Tc-99m-HDRBC scintigraphy in this context.