Chronic progressive lymphoedema (CPL) is a deteriorating disease affecting some large draught horse breeds, including Belgian draught horses (De Cock et al, 2003; Ferraro, 2001). Systemic failure of the lymph system and the skin elastic network are acausative factor (De Cock et al., 2006a; De Cock et al., 2006b). A genetic component is suggested (De Cock et al, 2006a; Gebu-rek et al., 2005). Cutaneous changes and deformations of the lower limbs result from reduced lymphatic drainage. Clinical signsmay appear early (less than 2 yrs) and mostly aggravate through life, often ending with severe disability justifying euthanasia (De Cock et al, 2003; Ferraro, 2001). Secondary infections often affect disease progression and complicate diagnosis (De Cocket al, 2003; Geburek et al, 2005). Since distinct symptoms may only appear after introduction into breeding programs, early detection of susceptible animals would tremendously help genetic selection.
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