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Erratum: Effectiveness of four-corner arthrodesis with use of a locked dorsal circular plate (Clinical Orthopaedics and Related Research)

机译:勘误:使用锁定的背侧圆板进行四角关节固定术的有效性(临床骨科及相关研究)

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摘要

Early diagnosis of dengue, the most common mosquito-borne disease globally, remains challenging. Dengue presents initially as undifferentiated fever, with symptoms becoming more pathognomonic in the later stages of illness. This limits the timeliness in the delivery of appropriate supportive interventions. Laboratory tests are useful for diagnosis although the short-lived viremia and the presence of secondary infection with one of the four heterologous viral serotypes collectively complicate the choice and interpretation of laboratory tests. In this article, the authors review the various approaches for diagnosis of dengue and discuss the appropriate tests to use, including when a dengue vaccine, which is in the late stages of development, is licensed for use. The ensuing reduced dengue prevalence could make diagnosis for vaccine efficacy and escape-mutant monitoring even more challenging.
机译:登革热(全球最常见的蚊媒传播疾病)的早期诊断仍然具有挑战性。登革热最初表现为未分化的发烧,在疾病的后期阶段症状变得更加病态化。这限制了提供适当的支持性干预措施的及时性。尽管短期病毒血症和四种异源病毒血清型之一的继发感染的存在共同使实验室测试的选择和解释复杂化,实验室测试对于诊断还是有用的。在本文中,作者回顾了诊断登革热的各种方法,并讨论了适当的测试方法,包括何时才可以使用处于发展后期的登革热疫苗。随之而来的登革热流行率的降低可能使疫苗效力的诊断和逃逸突变监测变得更具挑战性。

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