Purpose: To retrospectively evaluate the feasibility, safety, and effectiveness of computed tomography (CT)-guided percutaneous microwave ablation (MWA) in patients with bone metastases. Materials and Methods: Twenty-one patients with metastatic bone lesions were treated in 18 MWA sessions. In patients whose lesions contained fractures, or who had a high risk for fracture (48%; n = 10), MWA was followed by cementoplasty with polymethylmethacrylate injection. The positioning of the MWA antenna into the tumor was guided by CT. Treatments were performed under conscious sedation. All patients underwent clinical (self-reported Brief Pain Inventory [BPI]; scale from 0 to 10) and radiologic evaluation at baseline and 1 month after the procedure. The reported results are data from baseline to a follow-up period of 3 months. Results: There were no complications. A reduction of pain and improvement in quality of life was observed in all patients as measured by BPI score. On average, the mean BPI score during the 3-month follow-up period was reduced by 92% (41%-100%). Thirteen of 18 patients (72%) were symptom-free, four patients (22%) were still symptomatic but with 85% lower average BPI scores (41%-95%), and one patient (6%) experienced a recurrence of symptoms. Conclusions: Preliminary results suggest that MWA of bone metastases is a well tolerated, safe, and effective procedure. However, its efficacy still remains to be determined by medium- and long-term studies. ? 2013 SIR.
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机译：目的：回顾性评估计算机断层扫描（CT）引导的经皮微波消融（MWA）在骨转移患者中的可行性，安全性和有效性。材料和方法：18例MWA疗程对21例转移性骨病变患者进行了治疗。对于病变包含骨折或有高骨折风险（48％; n = 10）的患者，在进行MWA后再行注水泥和聚甲基丙烯酸甲酯注射。 MWA天线在肿瘤中的定位由CT引导。在清醒镇静下进行治疗。所有患者均在基线和手术后1个月接受临床（自我报告的简短疼痛清单[BPI];范围从0至10）和放射学评估。报告的结果是从基线到3个月随访期的数据。结果：无并发症。通过BPI评分，在所有患者中均观察到疼痛减轻和生活质量改善。平均而言，在3个月的随访期间，平均BPI得分降低了92％（41％-100％）。 18名患者中有13名（72％）无症状，四名患者（22％）仍然有症状，但平均BPI得分降低了85％（41％-95％），一名患者（6％）出现了症状复发。结论：初步结果表明，骨转移的MWA是一种耐受良好，安全且有效的方法。但是，其疗效仍有待中长期研究确定。 ？ 2013年SIR。
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