Role of capsule endoscopy as a screening tool for colorectal cancer

摘要

Colon capsule endoscopy is currently under evaluation to become a noninvasive colorectal cancer screening test. The sensitivity and specificity of colon capsule endoscopy for colorectal polyps and cancer are improving with ongoing technical refinements to the capsule and recording device, with sensitivity as high as 84% for polyps greater than 1 mm in size. Specificity for smaller polyps, however, remains suboptimal. Colon capsule endoscopy requires extensive bowel preparation to ensure adequate colon cleansing and complete colonic evaluation. The complication rate for colon capsule endoscopy is unclear, but may be lower than that for small bowel capsule endoscopy. The role of colon capsule endoscopy in colorectal cancer screening has not been fully defined, as technical, logistical and implementation issues remain.