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Adaptive-optics imaging of human cone photoreceptor distribution

机译:人体锥体感光细胞分布的自适应光学成像

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We have used an adaptive-optics scanning laser ophthalmoscope to image the cone photoreceptor mosaic throughout the central 10 deg-12 deg of the retina for four normal subjects. We then constructed montages of the images and processed the montages to determine cone locations. Cone densities range from approximately 10,000 cones/mm~(2) at 7 deg to 40,000 cones/mm~(2) at 1 deg. The smallest cones were not resolved in the center of the fovea. From the locations of the cones we also analyzed the packing properties of the cone mosaic, finding that all four subjects had a slight cone streak of increased cone density and that, in agreement with previous studies using different approaches, the packing geometry decreased in regularity from the fovea toward the periphery. We also found variations in packing density between subjects and in local anisotropy across retinal locations. The complete montages are presented for download, as well as the estimated cone locations.
机译:我们已经使用自适应光学扫描激光检眼镜对四个正常对象的整个视网膜中央10度到12度成像锥形感光体镶嵌图像。然后,我们构造图像的蒙太奇并处理蒙太奇以确定圆锥位置。圆锥体的密度范围从7度的大约10,000锥/ mm〜(2)到1度的40,000锥/ mm〜(2)。最小的视锥未在中央凹中央分离。从视锥的位置,我们还分析了视锥镶嵌物的填充特性,发现所有四个对象的视锥条纹略有增加,视锥密度增加,并且与先前使用不同方法的研究一致,填充几何形状自中央凹向外围。我们还发现受试者之间的堆积密度以及整个视网膜位置的局部各向异性存在差异。完整的蒙太奇以及估计的圆锥位置都将提供下载。

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