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首页> 外文期刊>Journal of the Optical Society of America, A. Optics, image science, and vision >Feature-based filter design for resolution enhancement of known features in microscopy
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Feature-based filter design for resolution enhancement of known features in microscopy

机译:基于特征的滤镜设计,用于增强显微镜中已知特征的分辨率

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摘要

We present a new feature-based design concept for filter design in which a filter is designed specifically to image a known feature with dimensions lower than the optical resolution of the system. Unlike the conventional filter design based on focal spot engineering, we use the complete response of the microscope to form a resolution factor and consider minimizing the resolution factor as the design goal. We consider three design goals (i.e., resolution factors) based on the system response and show that a feature matching approach is more suitable in practice. It is shown that a three-bar pattern and grid of square dots of critical dimension, 0.08 lambda, can be resolved using a simple two-layer feature-based filter designed for radially polarized illumination in aplanatic solid immersion lens microscopy. An example that requires a more complex filter is also shown. Applicability of the concept of feature-based filter design in diverse microscopy scenarios is discussed as well. (C) 2014 Optical Society of America
机译:我们提出了一种新的基于特征的滤镜设计概念,其中专门设计了滤镜以成像尺寸小于系统光学分辨率的已知特征。与基于焦点工程的常规滤波器设计不同,我们使用显微镜的完整响应来形成分辨率因子,并考虑将分辨率因子最小化作为设计目标。我们基于系统响应考虑了三个设计目标(即分辨率因子),并表明特征匹配方法在实践中更合适。结果表明,可以使用简单的两层基于特征的滤光片解决三尺寸图案和临界尺寸为0.08λ的正方形点的网格,该滤光片设计用于非平面固体浸没透镜显微镜中的径向偏振照明。还显示了一个需要更复杂的过滤器的示例。还讨论了基于特征的滤镜设计概念在各种显微镜下的适用性。 (C)2014年美国眼镜学会

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