Synthesis of 2, 4-diaryl-1, 5-benzodiazepines and 2, 4-diaryl-2, 3-dihydro-1, 5-benzothiazepines

摘要

Various 2, 4-disubstituted-1, 5-benzodiazepines have been prepared by condensing 1, 3-diones with o-phenylenediamine, and 2, 4-diaryl-1, 5-benzodiazepines and 2, 4-diaryl-2, 3-dihydro-1, 5-benzothiazepines have been prepared by condensing hydroxychalcone and o-aminothiophenol in boiling dry xylene and acetic acid medium.