Peripopillorv nerve fibre layer thickness ond moculor thickness in children with anisometfopic omblyopio ollending a referral centre' in Castern indict

摘要

To study the macular thickness and peripaplllary nerve fibre layer thickness in children with ani-sometropic amblyopia, a prospective non-randomised case series study was undertaken among 39 children (25 boys and. 14 girls) aged between 5 and 16 years. This study was carried out between . January 2010 and April 2011. The peripapiliary retinal nerve fibre layer (RNFL) thickness and macylar -layer thickness was measured using optical coherence tomography (QCT), the RNFL thickness and the macular layer thickness of the amblyopic eye was assessed and compared to the normal eye of the same subject. It was found that macular layer thickness In the amblyopic eye was greater than that of the macular thickness In the normal eye. The mean macular layer thickness in the amblyopic eyes was 229.589 pm with a standard deviation of +- 31,9149 pm.The mean macular layer thickness in the normal eyes of these children was 206.8717 pm with a standard deviation of +-28.490 pm, the p-value was 0.00141 which is much lesser than 0.005 and hence is strongly statistically significant. However the mean RNFL thickness in the amblyopic eye was 104.454 um with a standard deviation of +-22.244 pm. The mean RNFL thickness of the normal eye was 108.2746 pm with a SD of +-19.370 pm.The p-vaiue in ■ this case being 0.4246 which is statistically insignificant. It is conducted that macylar layer .thickness is raised in the amblyopic eye of children with anisometropic amblyo'pia though the RNFL thickness is not.