Bromination of cholest-4-en-3,6-dione with N-bromosuccmimide in chloroform

摘要

The reaction of cholest-4-en-3,6-dione (1) with N-bromosuccinimide in chloroform furnishes four compounds which have been identified as 2,7α-dibromo-choIest-1,4-dien-3,6-dione (2), 2,2,7α-tribromo-cholest-4-en-3,6-dione (3), 2α, 7α-dibromo-cholest-4-en-3,6-dione (4) and 2,2-dibromo-7-hydroxyl choiest-4-en-3,6-diune (5) by spectroscopic analyses.