Application of silica vanadic acid [SiO_2-VO(OH)_2] as a heterogeneous and recyclable catalyst for oxidative aromatization of Hantzsch 1,4-dihydropyridines at room temperature

摘要

A simple method for the oxidative aromatization of Hantzsch 1,4-dihydropyridines to the corresponding pyridines is described using hydrogen peroxide as green oxidant and silica vanadic acid as catalyst in acetonitrile at room temperature. The catalyst can be easily recovered and reused for 15 reaction cycles without considerable loss of activity.