Stereocontrolled synthesis of glucosidic damascenone precursors

摘要

A stereocontrolled synthesis of optically active beta-D-glucopyranosides 7-10 and 11-14, glucosidic damascenone precursors, was accomplished utilizing an asymmetric transfer hydrogenation to alpha,beta-acetylenic ketones catalyzed by chiral ruthenium complexes as the key step.