Friedel-Crafts reactions of a sulfonyl-substituted vinylic epoxide with various aromatics

摘要

The phenylsulfonyl-substituted vinylic epoxide 1 was allowed to react with BF_3 centre dot OEt_2 and various aromatics. A highly regioselective but moderately stereoselective mono-Friedel-Crafts reaction occurred which led to products 2 (Table 1). The fluorine-containing compounds 3a-b and 4 were obtained as side products.