Synthesis and characterization of novel 1, 3-selenazine derivatives. BF_3 centre dot Et_2O-assisted reaction of primary selenoamides with #alpha#, #beta#-unsaturated ketones

摘要

Reaction of primary selenoamides with #alpha#, #beta#-unsaturated ketones in the presence of BF_3 centre dot Et_2O provided 5, 6-dihydro-4H-1, 3-selenazine derivatives in high yields. Among the 1, 3-selenazine diastereomers bearing two asymmetric carbons at the C4 and C6 positions, the cis form is predominant.