Polysulfonylated cyclodextrins. Part 11. Preparation and structural validation of three isomeric pentakis(6-O-mesitylsulfonyl)cyclomaltoheptaoses

摘要

Three isomers of cyclomaltoheptaose derivatives, 1a-c, which possess five mesitylenesulfonyloxy groups on their C-6 atoms, were prepared. Assignment of the regiosiomers was performed by their conversion into compounds containing five 3,6-anhydroglucose units followed by ~1H NMR analyses. The structures of the pentakis(3, 6-anhydro) derivatives were also confirmed by their derivation from the known bis(TBDMS) derivatives.