Report of 27 cases of naevus spilus in 2134 patients with melanoma: is naevus spilus a risk marker of cutaneous melanoma?

摘要

We reported the experience of the Melanoma Unit of University Hospital of Spedali Civili of Brescia about the incidence of naevus spilus (NS) in the 2134 patients in follow-up for melanoma and the analysis of the risk that melanoma originated in NS, especially in patients who were already affected by this cutaneous tumour, with the intent to underline the importance of clinical monitoring. Naevus spilus is characterized by numerous small, darkly pigmented speckles, which could appear on a background of tarnish-brown hyperpigmentation. There are numerous different denominations for this skin lesion: 'naevus spilus', 'naevus on naevus', 'spotty naevus', 'speckled lentiginous naevus', 'speckled naevus spilus'. It is a relatively uncommon condition, it appeared in 2% of the population. Lesions are benign and they may be noted at birth or have their onset in early infancy or childhood.