Chemical Components and Their Bioactivities of Artemisia austro-yunnanensis

摘要

Artemisia austro-yunnanensis is a semi-herbaceous shrub, distributed in the tropical and subtropical areas. In this study, ten compounds were isolated from ethyl acetate fraction of its whole plant for the first time, and identified to be 7-(3-ethoxy-5-methoxyphenyl) propane-7,8,9-triol (1), secoisolariciresinol (2), (+)-pinoresinol (3), syringaresinol (4), eugenyl-O-beta-D-glucopyranoside (5), benzyl-O-beta-D-glucopyranoside (6), p-hydroxy-benzaldehyde (7), vanillin (8), syringaldehyde (9), 3-hydroxy-l-(4-hydroxy-3, 5-dimethoxyphenyl)-1-propanone (10) on the basis of ESI-MS and NMR spectra. This is the first report the occurrence of 1 from the family Asteraceae, whereas 2, 5 and 6 from the genus Artemisia. Meantime, all the isolates (1-10) were evaluated for their anti-oxidative and inhibiting neutrophil elastase activities by the bioassays in vitro.