Facile Synthesis and Herbicidal Evaluation of 2-Aryl-4H-3, l-benzoxazin-4-ones

摘要

The present work deals with the synthesis of 4H-3,l-benzoxazin-4-ones carrying an aryl functional group at position-2. Synthesized compounds tested for herbicidal activity at three different doses (500 μg/mL, 50 μg/mL and 5μg/mL). Most of the compounds exhibited significant herbicidal activity against Lemna aequinocitalis welv. at higher dose (500 μg/mL). Among the tested compounds 2-phenyl-4H-3,l-benzoxazin-4-one (3a) and 2-(3-chlorophenyl)-4H-3,l-benzoxazin-4-one (31) completely inhibited the plant growth at 500 and 50 μg/mL concentrations. All the synthetic compounds were characterized by FT-IR, ~1H NMR, EI-MS and elemental analysis.