O-6. Diffuse proliferative glomerulonephritis does not determine the worst outcome in childhood onset lupus nephritis: a 22-year experience in a single center

摘要

Introduction: Lupus nephritis (LN) is the major indicator of morbidity and mortality in systemic lupus erythematosus (SLE). Many studies have found a significantly worse patient survival rate in patients with LN class IV than patients with other LN classes. Objective: To describe the severity and outcomes of LN in a group of Thai children. Methods: We retrospectively reviewed the patient files of children diagnosed with SLE aged < =18 years in Songklanagarind Hospital, Southern Thailand, from 1985 to 2007. Results: Of 216 SLE patients, 180 had renal biopsy results, and the others were excluded from analysis.