Patient burden of moderate to severe atopic dermatitis (AD): Insights from a phase 2b clinical trial of dupilumab in adults

Simpson Eric L.; Bieber Thomas; Eckert Laurent; Wu Richard; Ardeleanu Marius; Graham Neil M. H.; Pirozzi Gianluca; Mastey Vera

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Patient burden of moderate to severe atopic dermatitis (AD): Insights from a phase 2b clinical trial of dupilumab in adults

机译：中重度特应性皮炎（AD）的患者负担：dupilumab成人2b期临床试验的见解

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摘要

Background: The adult burden of atopic dermatitis (AD) is poorly characterized.

机译：背景：成人特应性皮炎（AD）的负担特征不清。

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来源
《Journal of the American Academy of Dermatology》 |2016年第3期|共8页
作者
Simpson Eric L.; Bieber Thomas; Eckert Laurent; Wu Richard; Ardeleanu Marius; Graham Neil M. H.; Pirozzi Gianluca; Mastey Vera;
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原文格式 PDF
正文语种 eng
中图分类皮肤病学与性病学;
关键词
adults; atopic dermatitis; burden of illness; patient-reported outcomes; pruritus; quality of life;

机译：成人;特应性皮炎;疾病负担;患者报告的结局;瘙痒症;生活质量;

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专利

1. Patient burden of moderate to severe atopic dermatitis (AD): Insights from a phase 2b clinical trial of dupilumab in adults [J] . Simpson Eric L., Bieber Thomas, Eckert Laurent, Journal of the American Academy of Dermatology . 2016,第3期

机译：中重度特应性皮炎（AD）的患者负担：dupilumab成人2b期临床试验的见解
2. JAAD Game Changers: Dupilumab therapy provides clinically meaningful improvement in patient-reported outcomes (PROs): A phase IIb, randomized, placebo-controlled, clinical trial in adult patients with moderate to severe atopic dermatitis (AD) [J] . Lake Eden Journal of the American Academy of Dermatology . 2019,第4期

机译：JAAD游戏变化器：杜帕里姆治疗在患者报告的结果（专业人士）中提供临床有意义的改善：成年患者中度至严重特应性皮炎（广告）的成人患者中的IIB，随机，安慰剂控制，临床试验
3. Dupilumab therapy provides clinically meaningful improvement in patient-reported outcomes (PROs): A phase IIb, randomized, placebo-controlled, clinical trial in adult patients with moderate to severe atopic dermatitis (AD) [J] . Simpson Eric L., Gadkari Abhijit, Worm Margitta, Journal of the American Academy of Dermatology . 2016,第3期

机译：Dupilumab治疗可为患者报告的结局（PRO）提供临床上有意义的改善：一项针对中度至重度特应性皮炎（AD）成年患者的IIb期，随机，安慰剂对照的临床试验
4. Clinical Improvement and Immunological Changes of Atopic Dermatitis in Patients Undergoing Subcutaneous Immunotherapy with Depigmented Polymerized House Dust Mite Allergens [C] . C. Bussmann, AJ. Hart, S. Vrtala, Collegium Internationale Allergologicum . 2007

机译：用沉淀聚合房屋粉尘螨过敏原患者检查患者特应性皮炎的临床改善和免疫变化
5. Communication preferences, expectations of benefit, and symptom burdens among advanced cancer patients and partners during patient participation in phase I trials [D] . Hlubocky, Fay J. 2010

机译：患者参加I期试验期间，晚期癌症患者及其伴侣之间的沟通偏好，受益期望以及症状负担
6. Dupilumab Improves General Health-Related Quality-of-Life in Patients with Moderate-to-Severe Atopic Dermatitis: Pooled Results from Two Randomized Controlled Phase 3 Clinical Trials [O] . Eric L. Simpson 2017

机译：Dupilumab改善中度至重度特应性皮炎患者的一般健康相关生活质量：两项随机对照三期临床试验的汇总结果
7. Patient burden of moderate to severe atopic dermatitis (AD): Insights from a phase 2b clinical trial of dupilumab in adults [O] . Simpson Eric L., Bieber Thomas, Eckert Laurent, 2016

机译：中重度特应性皮炎（AD）的患者负担：成人dupilumab 2b期临床试验的见解

Patient burden of moderate to severe atopic dermatitis (AD): Insights from a phase 2b clinical trial of dupilumab in adults

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