Hematopoietic stem cell transplantation for primary cutaneous gamma delta T-cell lymphoma and refractory subcutaneous panniculitis-like T-cell lymphoma

摘要

Background: The panniculitic T-cell lymphomas (TCLs) comprise 2 distinct entities, alpha beta subcutaneous panniculitis-like TCL (SPTCL) and the gamma delta cutaneous TCLs with pannicular involvement primary cutaneous gd (PCGD)-TCL. Although outcomes for most patients with SPTCL are favorable, those with PCGD-TCLs generally have an inferior outcome, and treatment strategies have not been well defined. Allogeneic hematopoietic stem cell transplantation (HSCT) has been shown to be a potentially curative strategy in aggressive TCLs and in refractory and advanced-stage mycosis fungoides.