Papular mycosis fungoides: a variant of mycosis fungoides or lymphomatoid papulosis?

摘要

To the Editor: We would like to comment on the article by Kodama et al in the April 2005 issue of the Journal. Kodama and coworkers describe 6 patients with a papular variant of mycosis fungoides (MF). The evidence they provide that this is a clinical variant of MF are as follows: (1) histopathologic features compatible with MF were found in skin biopsy specimens from all patients; (2) typical patch lesions of MF subsequently developed in 2 of the patients; and (3) none of the patients had findings that characterize conditions that might be confused with papular MF (ie, there was an absenceneoplastic cells or response to immunoregulatoiy cytokines like transforming growth factor-beta rather than a difference in pathogenesis.