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摘要

Medical records of 45 English Springer Spaniels with idiopathic epilepsy were reviewed. Median age at the onset of seizures was 3 years; hpwever, 9 (20%) dogs were between 5 and 6 years old at the time of the onset of seizures. Twenty-one (47%) dogs had generalized seizures, and 24 (53%) had focal onset seizures. Results of segregation analysis were consistent with partially penetrant autosomal recessive or polygenic inheritance. Simulated linkage indicated that-there was a 58% chance of obtaining suggestive linkage with the available pedigrees.
机译:回顾了45例英国史宾格犬特发性癫痫的病历。癫痫发作的中位年龄为3岁;癫痫发作时,有9只(20%)狗的年龄在5至6岁之间。二十一只(47%)的狗出现了全身性癫痫发作,而二十四只(53%)的狗出现了局部发作性癫痫发作。隔离分析的结果与部分渗透性常染色体隐性遗传或多基因遗传一致。模拟的关联表明-有58%的机会获得与可用谱系的暗示关联。

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