Prepartion and Properties of New Tetrafunctional Amphoteric Surfactants Bearing Amino, Carboxyl, and Hydroxyl Groups and an Ether Bond

摘要

New amphoteric surfactants of N-(3-alkoxy-2-hydroxypropyl-N-(2-hydroxyethyl)-beta-alanine (APA) have been synthesized. The fundamental surface-active propertis (critical micelle concentration and isoelectric point) and hemolysis tests were also investigated to examine the effects of differences in chain length of the alkoxy moiety. The hemolysis result of APA exhibited low constant values irrespective of the alkyhl chain length. The amphoteric APA surfactant was confirmed to have a mild effect on human microorganisms and to possess excellent surface-active properties. In addition, a speculative model of micelle configuration was estimated by semiempirical molecular orbital simulations.