Coupling of ionic liquid-based headspace single-drop microextraction with GC for sensitive detection of phenols

摘要

A headspace single-drop microextraction (SDME) based on ionic liquid (IL) has been developed for the gas chromatographic determination of phenols. The volume of IL microdrop used was 1 mu L. After extraction, the analytes were desorbed from the drop in the injection port and the involatile IL was withdrawn into the microsyringe. To facilitate the withdrawal of IL the upper diameter of the split inlet liner was enlarged to some extent. Some parameters were optimized for the determination of phenols. Under the selected conditions, i.e., desorption for 100 s at 210 degrees C after extraction for 25 min at 50 degrees C in solutions (pH 3) containing 0.36 g/mL sodium chloride, the LODs, RSDs, and the average enrichment factors of phemols were 0.1 - 0.4 ng/mL, 3.6 - 9.5% (n = 5), and 35 - 794, respectively. The proposed procedure was applied to the determination of phenols in lake water and wastewater samples, and the spiked recoveries were in the range of 81 - 111 % at a spiked level of 0.4 mu g/mL. This method is a promising alternative for the sensitive determination of phenolic compounds.