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Illustrative assessment of human health issues arising from the potential release of chemotoxic substances from a generic geological disposal facility for radioactive waste

机译:对可能从通用地质处置设施中释放放射性废物的化学有毒物质潜在释放所引起的人类健康问题的说明性评估

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摘要

Many countries have a programme for developing an underground geological disposal facility for radioactive waste. A case study is provided herein on the illustrative assessment of human health issues arising from the potential release of chemotoxic and radioactive substances from a generic geological disposal facility (GDF) for radioactive waste. The illustrative assessment uses a source-pathway-receptor methodology and considers a number of human exposure pathways. Estimated exposures are compared with authoritative toxicological assessment criteria. The possibility of additive and synergistic effects resulting from exposures to mixtures of chemical contaminants or a combination of radiotoxic and chemotoxic substances is considered. The case study provides an illustration of how to assess human health issues arising from chemotoxic species released from a GDF for radioactive waste and highlights potential difficulties associated with a lack of data being available with which to assess synergistic effects. It also highlights how such difficulties can be addressed.
机译:许多国家制定了开发放射性废物地下地质处置设施的计划。本文提供了一个案例研究,该案例研究是对人类健康问题的说明性评估,该评估是由于可能从放射性废物的通用地质处置设施(GDF)释放化学毒性和放射性物质而引起的。说明性评估使用了一种源-途径-受体方法,并考虑了许多人类暴露途径。将估计的暴露量与权威的毒理学评估标准进行比较。考虑了由于暴露于化学污染物混合物或放射毒性和化学毒性物质的组合而导致的加性和协同效应的可能性。该案例研究说明了如何评估由GDF释放出的放射性废物产生的化学毒性物质引起的人类健康问题,并着重指出了与缺乏可用于评估协同效应的数据有关的潜在困难。它还强调了如何解决这些困难。

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