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首页> 外文期刊>Journal of plastic, reconstructive & aesthetic surgery: JPRAS >Management of complex melanomas of head and neck region.
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Management of complex melanomas of head and neck region.

机译:头颈部复杂黑色素瘤的治疗。

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Though many of the melanomas encountered in the head and neck region are amenable to simple excision and direct closure or skin grafts, there is a subset of patients who are deemed complex cases in view of the large size of the tumour, depth of invasion or proximity to aesthetically and functionally important structures. This was a retrospective study which looked at complex melanomas of the head and neck region treated in the last 10 years. There were a total of 19 cases, including four women and 15 men. Their ages ranged from 59 to 83 years (mean: 69 years). The Breslow thickness of these tumours ranged from 1 to 40 mm, with an average of 9 mm. The resectional procedures used herein included wide local excision (15 patients), wide excision with partial maxillectomy (one patient), wide excision with total maxillectomy (one patient) and orbital exenteration (two patients). Neck dissections were performed in 12 cases and parotidectomy was performed in five cases. Reconstruction was performed using local (two cases), regional (five cases) and free flaps (11 cases) in a total of 18 cases. There were four complications, including two nerve injuries during neck dissection (vagus and marginal mandibular nerve). Four patients died during follow-up due to metastatic disease and had a median survival of 3.5 years (range: 2-8 years, mean: 3 years). One patient is alive with recurrent disease and distant metastases 4 years after the original surgery. The remaining 14 patients are alive and free of recurrence with a follow-up period ranging from 2 to 7 years (median: 4.5 years).
机译:尽管在头颈部区域遇到的许多黑色素瘤都适合简单切除和直接闭合或皮肤移植,但由于肿瘤的大小,侵袭深度或邻近性,有一部分患者被认为是复杂病例在美学和功能上重要的结构。这是一项回顾性研究,研究了过去10年中治疗的头颈部区域复杂的黑色素瘤。共有19例,其中4名女性和15名男性。他们的年龄为59至83岁(平均69岁)。这些肿瘤的Breslow厚度范围为1至40 mm,平均为9 mm。本文使用的切除程序包括局部广泛切除(15例),部分上颌骨切除术(1例),全上颌骨切除术(1例)和眼眶脱离(2例)。颈清扫术12例,腮腺切除术5例。总共18例使用局部(2例),区域(5例)和游离皮瓣(11例)进行了重建。有四种并发症,包括在颈清扫过程中有两次神经损伤(迷走神经和下颌缘神经)。 4例患者在随访期间因转移性疾病死亡,中位生存期为3。5年(范围:2-8年,平均:3年)。一名患者在最初手术后的4年内还活着,患有复发性疾病并发生远处转移。其余14例患者仍活着且无复发,随访期为2至7年(中位数:4.5年)。

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