FUNCTIONAL EFFECTS OF BOTULINUM TOXIN TYPE-A TREATMENT AND SUBSEQUENT STRETCHING OF SPASTIC CALF MUSCLES: A STUDY IN PATIENTS WITH HEREDITARY SPASTIC PARAPLEGIA

摘要

Objective: Although calf muscle spasticity is often treated with botulinum toxin type-A, the effects on balance and gait are ambiguous. Hereditary spastic paraplegia is characterized by progressive spasticity and relatively mild muscle weakness of the lower limbs It is therefore a good model to evaluate the functional effects of botulinum toxin type-A.