Post-exposure prophylaxis for hepatitis A: immune globulin, vaccine or both?

摘要

Hepatitis A (HAV) causes one of the most common infectious diseases in the world and may produce clinical conditions ranging from a-symptomatic infection to acute liver failure. Hepatitis A infection is an endemic problem in most African and South American Countries, meanwhile its incidence has largely declined over the last 2 decades in Western Europe and USA [1,2].