The Retention Behavior of Selected Macrocyclic Antibiotics on Polyamide TLC Plates

摘要

The chromatographic behavior of six macrocyclic antibiotics (erythromycin, troleanodomycin, tylosin, vancomycin, rifamycin B, and rifampicin) has been examined on Polyamide 11F-254 TLC plates as stationary phase with five binary solvent mixtures (methanol-water, ethanol-water, propanol-water, acetontrile-water, and tetrahydrofuran-water) as mobile phases in which the concentration of the organic modifier was from 0 to 100% (v/v). Chromatographic retention data and a possible retention mechanism are discussed.