Antitumoral Effect of L. inermis in Mice with EAC

摘要

In recent years, prophylactic usage of natural products and tendency to resort to alternative medicine has increased rapidly. Henna (Lawsonia sp.) has been used not only cosmetically but also medicinally in Turkish population. Among the studies of henna's anrifungai, anti-microbial, tuberculostatic and antitumoral effects come on the science. In this study, we planned to research the effect of Lawsoniainennis that is an oxidant agent against development of cancer, by constituting peritonitis carcinomatous with Ehrlich ascites cells. The animals were divided to three groups and Lawsonia inermis extract and tap water were given to mice for 5 days. After 5 days, all of animals were decapitated by cervical dislocation and their liver tissues were sampled to measure reduced glutathione (GSH) level. Mean Survival Time (MST) and Average Survival Time (AST) were calculated; peritoneal liquid pH was measured; Ehrlich Ascites Carcinoma (EAC) cells were counted with hemocytometer.