Bayesian-hierarchical pharmacokinetic/pharmacodynamic (PK/PD) model to characterize the exposure-QT effect relationship for decision making in early drug development

Dubois Vincent F. S.; Boulton Muriel; Bursi Roberta

首页> 外文期刊>Journal of Pharmacological and Toxicological Methods >Bayesian-hierarchical pharmacokinetic/pharmacodynamic (PK/PD) model to characterize the exposure-QT effect relationship for decision making in early drug development

【24h】

Bayesian-hierarchical pharmacokinetic/pharmacodynamic (PK/PD) model to characterize the exposure-QT effect relationship for decision making in early drug development

机译：贝叶斯递阶药代动力学/药效学（PK / PD）模型表征暴露-QT效应关系，用于早期药物开发中的决策

获取原文

获取原文并翻译 | 示例

获取外文期刊封面目录资料

开具论文收录证明 >>

文献代查 >>

文献数据库（团队版） >>

页面导航

著录项
引文网络
相似文献
相关主题

著录项

来源
《Journal of Pharmacological and Toxicological Methods》 |2016年第null期|共1页
作者
Dubois Vincent F. S.; Boulton Muriel; Bursi Roberta;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类药理学;
关键词

相似文献

外文文献
中文文献
专利

1. Bayesian-hierarchical pharmacokinetic/pharmacodynamic (PK/PD) model to characterize the exposure-QT effect relationship for decision making in early drug development [J] . Dubois Vincent F. S., Boulton Muriel, Bursi Roberta Journal of Pharmacological and Toxicological Methods . 2016,第Null期

机译：贝叶斯递阶药代动力学/药效学（PK / PD）模型表征暴露-QT效应关系，用于早期药物开发中的决策
2. PHARMACOKINETIC/PHARMACODYNAMIC (PK/PD) MODELING: AN INVESTIGATIONAL TOOL FOR DRUG DEVELOPMENT [J] . DHEERAJ GOPU, GOMATHI P International Journal of Pharmacy and Pharmaceutical Sciences . 2012,第Suppla3期

机译：药代动力学/药代动力学（PK / PD）建模：药物开发的研究工具
3. PHARMACOKINETICS, PHARMACODYNAMICS AND DRUG METABOLISM Influence of Plasma Protein Binding on Pharmacodynamics: Estimation of In Vivo Receptor Affinities of beta Blockers Using a New Mechanism-Based PK-PD Modelling Approach [J] . T.J. VAN STEEG, V.B. BORALLI, E.H.J. KREKELS Journal of pharmaceutical sciences. . 2009,第10期

机译：药代动力学，药物动力学和药物代谢对血浆蛋白结合的药效学影响：使用基于新机制的PK-PD建模方法估算β受体阻滞剂的体内受体亲和力
4. FPGA Implementation of a Pharmacodynamic and Pharmacokinetics (PK/PD) Model for Application in General Anesthesia [C] . Maria Camila Cardona García, David Alejandro Vallejo Santacruz, Daniel Felipe Valencia Vargas, IEEE ANDESCON Conference . 2018

机译：用于全身麻醉的药效和药代动力学（PK / PD）模型的FPGA实现
5. Mechanism-based pharmacokinetic/pharmacodynamic PK/PD modeling of corticosteroids and antiretrovirals. [D] . Fang, Jing. 2012

机译：皮质类固醇和抗逆转录病毒药物的基于机理的药代动力学/药效动力学PK / PD建模。
6. Pharmacokinetic-pharmacodynamic (PK-PD) modelling in non-steady-state studies and arterio-venous drug concentration differences. [O] . M Gumbleton, S Oie, D Verotta 1994

机译：非稳态研究中的药代动力学-药效学（PK-PD）模型和动静脉药物浓度差异。
7. PIH13 COST IMPLICATIONS OF DRUG-DRUG INTERACTIONS WITH HORMONAL CONTRACEPTIVES: A CONCEPTUAL FRAMEWORK BASED ON LINKED PHARMACOKINETIC-PHARMACODYNAMIC-PHARMACOECONOMIC (PK-PD-PE) MODELS [O] . M. Srinivasan, A. White, A. Chaturvedula, 2019

机译：药物 - 药物与激素避孕药的成本影响：基于链接药代动力学 - 药物动力学 - 药物经济学（PK-PD-PE）模型的概念框架

Bayesian-hierarchical pharmacokinetic/pharmacodynamic (PK/PD) model to characterize the exposure-QT effect relationship for decision making in early drug development

著录项

引文网络

相似文献

相关主题

期刊订阅