Target-Mediated Drug Disposition (TMDD) Population Pharmacokinetics (PopPK) Model Using the Quasi-Steady-State (QSS) Approximation of Alirocumab in Healthy Volunteers or Patients: Pooled Analysis of Randomized Phase I/II/III Studies

Djebli Nassim; Martinez Jean-Marie; Lohan Laura; Khier Sonia; Brunet Aurelie; Hurbin Fabrice; Fabre David

首页> 外文期刊>Journal of pharmacokinetics and pharmacodynamics >Target-Mediated Drug Disposition (TMDD) Population Pharmacokinetics (PopPK) Model Using the Quasi-Steady-State (QSS) Approximation of Alirocumab in Healthy Volunteers or Patients: Pooled Analysis of Randomized Phase I/II/III Studies

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Target-Mediated Drug Disposition (TMDD) Population Pharmacokinetics (PopPK) Model Using the Quasi-Steady-State (QSS) Approximation of Alirocumab in Healthy Volunteers or Patients: Pooled Analysis of Randomized Phase I/II/III Studies

机译：在健康志愿者或患者中使用拟定状态（QSS）近似的目标介导的药物处置（TMDD）群体药代动力学（PopPK）模型：I / II / III期随机研究的汇总分析

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来源
《Journal of pharmacokinetics and pharmacodynamics》 |2016年第suppla期|共2页
作者
Djebli Nassim; Martinez Jean-Marie; Lohan Laura; Khier Sonia; Brunet Aurelie; Hurbin Fabrice; Fabre David;
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正文语种 eng
中图分类药学;
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1. Target-Mediated Drug Disposition (TMDD) Population Pharmacokinetics (PopPK) Model Using the Quasi-Steady-State (QSS) Approximation of Alirocumab in Healthy Volunteers or Patients: Pooled Analysis of Randomized Phase I/II/III Studies [J] . Djebli Nassim, Martinez Jean-Marie, Lohan Laura, Journal of pharmacokinetics and pharmacodynamics . 2016,第Suppla期

机译：在健康志愿者或患者中使用拟定状态（QSS）近似的目标介导的药物处置（TMDD）群体药代动力学（PopPK）模型：I / II / III期随机研究的汇总分析
2. Target-Mediated Drug Disposition Population Pharmacokinetics Model of Alirocumab in Healthy Volunteers and Patients: Pooled Analysis of Randomized Phase I/II/III Studies [J] . Nassim Djebli, Jean-Marie Martinez, Laura Lohan, Clinical pharmacokinetics . 2017,第10期

机译：Alirocumab在健康志愿者和患者中的靶介导的药物置入群体药代动力学模型：随机阶段I / II / III研究的汇总分析
3. Population Pharmacokinetic Analysis of Alirocumab in Healthy Volunteers or Hypercholesterolemic Subjects Using a Michaelis-Menten Approximation of a Target-Mediated Drug Disposition ModelSupport for a Biologics License Application Submission: Part I [J] . Martinez Jean-Marie, Brunet Aurelie, Hurbin Fabrice, Clinical pharmacokinetics . 2019,第1期

机译：使用MICHAELIS-MENTEN近似对生物制剂许可申请提交的靶介导的药物处理模型的迈克莱斯 - 霉菌近似的人群药代动力学分析
4. Efficacy Analysis of Preservative-Free Tafluprost and Timolol in Open-Angle Glaucoma and OHT Patients in a Phase-III Study [C] . GrundenJ., Lupinacci R. International Symposium on Ocular Pharmacology and Therapeutics . 2013

机译：在第三阶段研究中，在开放角度荧光眼和OHT患者中无防腐型TaFluprost和蒂莫尔的疗效分析
5. Target-Mediated Drug Disposition Population Pharmacokinetics Model of Alirocumab in Healthy Volunteers and Patients: Pooled Analysis of Randomized Phase I/II/III Studies [O] . Nassim Djebli, Jean-Marie Martinez, Laura Lohan, -1

机译：健康志愿者和患者中Alirocumab的目标介导的药物处置人群药代动力学模型：随机I / II / III期研究的汇总分析
6. Target-Mediated Drug Disposition Population Pharmacokinetics Model of Alirocumab in Healthy Volunteers and Patients: Pooled Analysis of Randomized Phase I/II/III Studies [O] . Nassim Djebli, Jean-Marie Martinez, Laura Lohan, 2017

机译：健康志愿者和患者中Alirocumab的目标介导的药物处置人群药代动力学模型：随机I / II / III期研究的汇总分析

Target-Mediated Drug Disposition (TMDD) Population Pharmacokinetics (PopPK) Model Using the Quasi-Steady-State (QSS) Approximation of Alirocumab in Healthy Volunteers or Patients: Pooled Analysis of Randomized Phase I/II/III Studies

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