Inhibition of scytalone dehydratase in melanin biosynthesis by carpropamid, a novel rice blast controlling agent.

摘要

Using cell-free extracts of the rice blast pathogen, Magnaporthe grisea, it was demonstrated that carpropamid can inhibit dehydration of scytalone without affecting the biosynthesis of scytalone dehydratase in M. grisea. These results were confirmedby an analysis of the carpropamid inhibition of a recombinant scytalone dehydratase in Escherichia coli.