Differential Benefits of Amoxicillin-Metronidazole in Different Phases of Periodontal Therapy in a Randomized Controlled Crossover Clinical Trial

摘要

Background: The specific advantage of administering systemic antibiotics during initial, non-surgical therapy or in the context of periodontal surgery is unclear. This study assesses the differential outcomes of periodontal therapy supplemented with amoxicillin-metronidazole during either the non-surgical or the surgical treatment phase.