Flow-injection biamperometric direct determination of calcium dobesilate in irreversible couple system.

摘要

A flow-injection biamperometric method for direct determination of calcium dobesilate had been proposed based on biamperometric detection for irreversible couple. The detection was realized by coupling the oxidation of dobesilate at one platinum wire electrode with the reduction of MnO(4)(-) at another one with the applied potential difference of 0 V between two platinum wire electrodes. Dobesilate was determined in the range of 4.0x10(-6) to 1.0x10(-4) M with the detection limit of 8.0x10(-7) M (S/N=3). The relative standard derivation of 1.7% was obtained for 24 successive determinations of 4.0x10(-5) M dobesilate. The proposed method had been shown to be sensitive, simple and rapid.