Both the lay and professional media have increasingly focused on harm due to misuse of opioids in recent years. In the United States, we have seen the FDA implement a Risk Management and Mitigation Strategy (REMS) for long acting opioids, increasing numbers of reports of deaths from prescribed opioids, and calls for restraint in prescribing these strong analgesics due to mounting concerns about misuse. This journal has attempted to provide balanced discussions on these controversial issues for over a decade.
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