IgG4-related sclerosing disease: autoimmune pancreatitis (AIP) and IgG4-related cholangitis.

摘要

A 67 year-old man was admitted to our hospital for painless jaundice and deterioration of general condition. CT scan showed intrahepatic bile ducts (BD) dilatation, common BD stricture, and heterogeneity of pancreas. Laparotomic cholecystectomy revealed no cholangiocarci-noma, but sclerosing cholangitis lesions, and pancreatic biopsy showed no neoplastic cell but lymphoplasmocytic infiltration. Secondarily, magnetic resonance cholangiopancreato-graphy (MRCP) showed multiple stenoses and dilatations of common and intrahepatic BD, and of main pancreatic duct (Fig. 1), parietal BD enhancement, and global heterogeneity and hyperintensity of the pancreas. lgG4 levels were elevated in patient's serum (1.4g/L).