Ginkgolide B Protects Against Ischemic Stroke Via Modulating Microglia Polarization in Mice

Shu Zhao-Ma; Shu Xiao-Dong; Li Hui-Qin; Sun Yi; Shan Han; Sun Xi-Yang; Du Ren-Hong; Lu Ming; Xiao Ming; Ding Jian-Hua; Hu Gang

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Ginkgolide B Protects Against Ischemic Stroke Via Modulating Microglia Polarization in Mice

机译：银杏内酯B通过调节小鼠的小胶质细胞极化来预防缺血性卒中。

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AimGinkgolide B (GB) has shown neuroprotective effect in treating ischemic stroke, related to its property of anti-inflammation. Nevertheless, it is unclear whether GB is able to modulate microglia/macrophage polarization, which has recently been proven to be vital in the pathology of ischemic stroke.

机译：AimGinkgolide B（GB）在治疗缺血性中风方面显示出神经保护作用，与其抗炎特性有关。然而，目前尚不清楚GB是否能够调节小胶质细胞/巨噬细胞的极化，近来已被证明在缺血性中风的病理学中至关重要。

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来源
《CNS neuroscience & therapeutics》 |2016年第9期|共11页
作者
Shu Zhao-Ma; Shu Xiao-Dong; Li Hui-Qin; Sun Yi; Shan Han; Sun Xi-Yang; Du Ren-Hong; Lu Ming; Xiao Ming; Ding Jian-Hua; Hu Gang;
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正文语种 eng
中图分类神经病学与精神病学;
关键词
Ginkgolide B; Microglia; macrophage polarization; Platelet activator factor receptor; Stroke;

机译：银杏内酯B;小胶质细胞;巨噬细胞极化;血小板活化因子受体;中风;

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1. Ginkgolide B Protects Against Ischemic Stroke Via Modulating Microglia Polarization in Mice [J] . Shu Zhao-Ma, Shu Xiao-Dong, Li Hui-Qin, CNS neuroscience & therapeutics . 2016,第9期

机译：银杏内酯B通过调节小鼠的小胶质细胞极化来预防缺血性卒中。
2. Remote Limb Ischemic Postconditioning Protects against Ischemic Stroke via Modulating Microglia/Macrophage Polarization in Mice [J] . Dong Han, Jue Wang, Lulu Wen, Journal of immunology research. . 2021,第a期

机译：远程肢体缺血性后处理通过调节小鼠中的小胶质细胞/巨噬细胞极化来保护缺血性卒中
3. Melatonin protects against ischemic stroke by modulating microglia/macrophage polarization toward anti‐inflammatory phenotype through STAT3 pathway [J] . Zong‐Jian Liu, Yuan‐Yuan Ran, Shu‐Yan Qie, CNS neuroscience & therapeutics. . 2019,第12期

机译：通过STAT3途径调节微血花症/巨噬细胞极化，通过调节微血管瘤/巨噬细胞极化来保护褪黑素免受缺血性卒中
4. Sulfated Chondroitin Sulfate Glycosaminoglycan Hydrogel Carriers Improve Transplanted Cell Survival and Enhance Regeneration after Ischemic Stroke in Mice [C] . Myles R. McCrary, Kaleena Jesson, Gemy Sethaputra, Society for Biomaterials annual meeting and exposition . 2018

机译：硫酸软骨素硫酸糖胺聚糖水凝胶载体改善小鼠缺血性中风后的移植细胞存活并增强再生。
5. Inflammatory mechanisms after thromboembolic ischemic stroke in mice [D] . Abulafia, Denise P. 2008

机译：小鼠血栓栓塞性缺血性中风后的炎症机制
6. Ginkgolide B Protects Against Ischemic Stroke Via Modulating Microglia Polarization in Mice [O] . Zhao‐Ma Shu, Xiao‐Dong Shu, Hui‐Qin Li, 2016

机译：银杏内酯B通过调节小鼠的小胶质细胞极化来预防缺血性卒中。
7. Hypothermia Protects Mice Against Ischemic Stroke by Modulating Macrophage Polarization Through Upregulation of Interferon Regulatory Factor-4 [O] . Xinyuan Yu, Yanping Feng, Renzhong Liu, 2021

机译：通过调节干扰素调节因子-4的上调调节巨噬细胞极化，体温过低来保护小鼠免受缺血性卒中的影响

Ginkgolide B Protects Against Ischemic Stroke Via Modulating Microglia Polarization in Mice

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