Population structure of Biomphalaria glabrata, intermediate snail host of Schistosoma mansoni in Guadeloupe island, using RAPD markers

摘要

Nine populations of Biomphalaria glabrata were sampled in 1992 and 1994 in Guadeloupe, which is a focus of schistosomiasis mansoni. Genetic polymorphism was studied using random amplified polymorphic DNA (RAPD) markers. The detected polymorphism waslow with 11 polymorphic markers. A canonical analysis of the polymorphism showed a significant and large differentiation between the 9 populations which originated within a restricted area of 45 km2. A Mantel t-test indicated a significant correlation between genetic differentiation and geographical distance. A significant but smaller differentiation between northern and southern groups was also observed using canonical analysis.