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Filtration characteristics of hollow fiber microfiltration membranes used in a specific double membrane bioreactor

机译:特定双膜生物反应器中使用的中空纤维微滤膜的过滤特性

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The performance of the microfiltration in a specifically designed membrane bioreactor operating under various transmembrane pressures with periodic backwashing was investigated for model media. These media were representative of some usual components of a fermentation medium: BSA solution (2g L~(-1)), yeast suspension (8 g L~(-1), dry mass) and a mixture of BSA/yeast (2 g L~(-1) /8 g L~(-1)). In this system, the separation was provided by a 0.1 μ m polysulfone hollow fiber membrane. The net permeate fluxes observed for yeast/BSA mixture were proportional to the transmembrane pressure applied (ΔP) but were less than those obtained with water osmosis, showing that, in spite of the periodic backwash, a small amount of irreversible fouling remained. This fouling can be assumed to be due to internal fouling by protein and/or external fouling by a residual yeast cake. Moreover, the net permeate flux obtained with the yeast/BSA mixture was higher than that obtained with the BSA alone, showing that a thin yeast cake probably acted as a primary filtration layer that could protect the polysulfone membrane against protein fouling. These experiments enable operating recommendations to be made for the use of this specific bioreactor concerning the transmembrane pressure value and the possible addition of inert particles.
机译:对于模型介质,研究了在特殊设计的膜生物反应器中的微滤性能,该膜生物反应器在各种跨膜压力下进行定期反洗。这些培养基代表了发酵培养基的一些常见成分:BSA溶液(2 g L〜(-1)),酵母悬浮液(8 g L〜(-1),干物质)和BSA /酵母的混合物(2 g L〜(-1)/ 8 g L〜(-1))。在该系统中,分离是通过0.1μm的聚砜中空纤维膜进行的。观察到的酵母/ BSA混合物的净渗透通量与所施加的跨膜压力成正比(ΔP),但小于水渗透法所获得的通量,表明尽管进行了定期反洗,但仍残留少量不可逆结垢。可以认为该结垢是由于蛋白质的内部结垢和/或残留的酵母饼引起的外部结垢。此外,用酵母/ BSA混合物获得的净渗透通量高于单独用BSA获得的净渗透通量,表明稀薄的酵母饼可能充当了初级过滤层,可以保护聚砜膜免受蛋白质污染。这些实验使得能够就该特定生物反应器的使用提出有关跨膜压力值和可能添加惰性颗粒的操作建议。

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