The Alpase of follicles was studied systematically during the period before and after ovulation in superpvulated rabbits. The locations and changes of follicular Alpase varied with the four kinds of physiological status before and after ovulation. Alpase activity was the highest at oestrus and started to drop at the beginning of ovulation, then it increased 15 h later and decreased slightly 39 h afterwards the beginning of ovulation. Alpase was found on the follicular basement membrane at oestrus. The synthesis of fiber in fibcrblasts was connected with Alpase activity.
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